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Filtered Search Results
Medchemexpress LLC Chrysoidine G (Solvent Orange 3 hydrochloride) | 532-82-1 | 250 MG
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Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye) used for the construction of most textile dyestuffs and in synthetic industrial compounds. Its concentration can be determined by UV-Vis spectroscopy. This product is for research use only and not for sale to patients.
- Molecular weight: 248.71
- Formula: C12H13ClN4
- Appearance: Solid
- Color: Brown to black
- CAS number: 532-82-1
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Medchemexpress LLC Ethyl 3-hydroxybutyrate | 5405-41-4 | 99.99% | 132.16 | 50 G
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Ethyl 3-hydroxybutyrate is a fragrance found in wine and *Tribolium castaneum*. In vivo, Ethyl 3-hydroxybutyrate (300 mg/kg, ip, once daily for 28 days) increases 3-HB levels in serum, promotes TCA cycle and protein synthesis, improves metabolic homeostasis. Ethyl 3-hydroxybutyrate reduces inflammation responses and enhances antioxidant capacity, and alleviates cancer cachexia-associated skeletal muscle atrophy in CT26 xenograft mouse models.
- Increased the levels of 3-HB in serum and gastrocnemius muscle.
- Reduced weight loss, skeletal muscle atrophy, tumor weight.
- Improved mice survival.
- Reduced levels of IFN-γ and TGF-β in serum.
- Improved the structure of gastrocnemius muscle, partially restored the cross-sectional area of muscle fibers.
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Medchemexpress LLC N-carbamoyl-DL-aspartic acid | 923-37-5 | 99.92% | 50 MG
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N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is the analytical standard of N-Carbamoyl-DL-aspartic acid. This product is intended for research and analytical applications. It is a precursor of nucleic acid pyrimidines and has antitumor activities. The compound is a reference standard commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Used as a reference standard assay
- Intended for research and analytical applications
- Involved in fundamental biological processes as a precursor of nucleic acid pyrimidines
- Possesses potential therapeutic interest due to antitumor activities
- Commonly used in HPLC, GC, and MS research experiments
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Medchemexpress LLC 1-Naphthalenecarboxaldehyde, 2-hydroxy-, S-(4-methylphenyl)thiooxime | 906439-72-3 | 99.9% | 250 MG
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COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of 0.37 nM. It binds to the catalytic domain of PARG, which prolongs PARylation at DNA lesions and traps DNA repair factors. This compound efficiently kills PARP inhibitor-resistant cancer cells and induces lethality in cancer cells with DNA repair defects, exhibiting antitumor activity in xenograft mouse cancer models. It is intended for research use only.
- Potent and specific PARG inhibitor with an IC50 of 0.37 nM
- Binds to the catalytic domain of PARG (Kd=0.547 μM)
- Efficiently kills PARP inhibitor-resistant cancer cells
- Induces lethality in cancer cells with DNA repair defects
- Exhibits antitumor activity in xenograft mouse cancer models
- For research use only
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Medchemexpress LLC 1H-Pyrrole-2-carboxamide, N-(3-cyano-4-fluorophenyl)-1-methyl-4-[[[(1S)-2,2,2-trifluoro-1-methylethyl]amino]sulfonyl]- | 1638266-40-6 | 98.9% | 418.37 | 250 MG
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Bersacapavir is an HBV capsid assembly modulator that exerts a dual mechanism of action against both early and late stages of HBV infection. It forms complete genome-free empty capsids and inhibits de novo synthesis of cccDNA, making it useful in hepatitis B research.
- Enhances the rate and extent of HBV capsid assembly.
- Potently inhibits HBV replication in HepG2.117 and HepG2.2.15 cells.
- Exhibits additive to synergistic antiviral activity when combined with TDF or ETV.
- Reduces extracellular HBV DNA, intracellular HBV RNA, extracellular HBe/cAg, and extracellular HBsAg.
- Inhibits cccDNA formation when added to HBV-infected PHHs.
- Disrupts pre-formed mature HBV capsids.
- Can be dissolved in 10% DMSO and 90% corn oil for in vivo dissolution.
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Medchemexpress LLC 4-Azidobutylamine | 88192-20-5 | 98.0% | 114.15 | 250 MG
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4-Azidobutylamine is a PROTAC linker, characterized by its alkyl chain composition. It is utilized in the synthesis of PROTACs, which are molecules containing two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for a target protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Additionally, it is a click chemistry reagent containing an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PROTAC linker
- Click chemistry reagent
- Contains an Azide group for CuAAc and SPAAC reactions
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Medchemexpress LLC 6-Hydroxytropinone | 5932-53-6 | 155.19 | 250 MG
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6-Hydroxytropinone is an alkaloid product that can be isolated from the roots of Atropa belladonna. This product is for research use only and has not been fully validated for medical applications.
- Alkaloid product
- Isolated from the roots of Atropa belladonna
- Solid appearance
- Yellow to brown color
- Store powder at -20°C for up to 3 years or 4°C for up to 2 years
- Store in solvent at -80°C for up to 6 months or -20°C for up to 1 month
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Medchemexpress LLC 1H-indole-2,3-dione, 1-(phenylmethyl)- | 1217-89-6 | MFCD00187663 | 96.4% | 237.26 g/mol | C15H11NO2 | 250 MG
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Benzylisatin is a biologically potent derivative of isatin used as a building block in medicinal chemistry research. It is commonly used as a precursor to synthesize biologically active Schiff bases and metal complexes and is supplied for biochemical assay and compound screening applications. The compound has CAS number 1217-89-6, molecular formula C15H11NO2, molecular weight 237.26 g/mol, and an analyzed purity of 96.39% by HPLC.
- Biologically potent isatin derivative for medicinal chemistry research
- Used to prepare Schiff bases and metal complexes
- Molecular formula C15H11NO2 and molecular weight 237.26 g/mol
- CAS number 1217-89-6 for unambiguous identification
- Analyzed purity 96.39% (HPLC)
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Cayman Chemical Tricosanoic Acid ethyl ester
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A saturated fatty acid ethyl ester; can be used as a standard for analysis of lipid mixtures
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Medchemexpress LLC Tranexamic acid impurity 1 | 1197-17-7 | MFCD19706018 | ≥98.0% | 157.21 g/mol | C8H15NO2 | 250 MG
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Tranexamic acid impurity 1 is a characterized impurity of the active pharmaceutical ingredient tranexamic acid, supplied for research and analytical purposes as a drug intermediate or impurity reference. The substance is provided with a certificate of analysis and recommended storage instructions for laboratory use.
- Used as an analytical reference or impurity standard.
- Purity: ≥98.0%.
- Chemical formula: C8H15NO2; molecular weight: 157.21 g/mol.
- Supplied in multiple pack sizes (e.g., 250 MG) for flexibility in experiments.
- Intended for research use only; not for clinical or diagnostic use.
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Medchemexpress LLC C12-iE-DAP hydrochloride | 1269619-57-9 | 538.07 | 10 MG
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C12-iE-DAP hydrochloride is the hydrochloride salt form of C12-iE-DAP, a biologically active peptide that acts as an agonist for NOD1. It is designed for high-speed applications and is suitable for laboratory centrifugation and storage.
- Molecular formula: C24H44ClN3O8
- Sequence: Lauroyl-γ-d-Glu-meso-diaminopimelic acid
- Target: NOD-like Receptor (NLR)
- Pathway: Immunology/Inflammation
- Solvent & solubility (in vitro): DMSO: 100 mg/mL (185.85 mM; need ultrasonic)
- Agonistic effects on NOD1
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eMolecules Pharmablock 4-(aminomethyl)benzamide hydrochloride 250mg 686935228 PBT1230-1 0 000 20188-40-3 MFCD07289058 186 640 C8H11ClN2O
Pharmablock 4-(aminomethyl)benzamide hydrochloride 250mg 686935228 PBT1230-1 0 000 20188-40-3 MFCD07289058 186 640 C8H11ClN2O
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Apexbio Technology LLC 2'-O-Methyl-5-methyl-UTP 10ul (100 mM)
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2 -O-Methyl-5-methyl-UTP is a chemically modified nucleoside triphosphate analogue designed to enhance resistance to nuclease degradation and improve annealing properties toward complementary RNA sequences Incorporation of this compound into RNA oligonucleotides increases binding affinity to target RNA strands enhances stability under physiological conditions and reduces immune recognition Based on these pharmacological properties 2 -O-Methyl-5-methyl-UTP holds research potential in the synthesis of RNA therapeutics gene silencing projects antisense technology development and other applications requiring long-lasting bioactivity and minimal immunogenic response
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Medchemexpress LLC H4 Receptor antagonist 1 | 848217-00-5 | 99.7% | 316.79 | 100 MG
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H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist with an IC50 of 19 nM. It is intended for research use only. In vitro studies demonstrate its activity against the H4 receptor at 19 nM IC50. In vivo, it exhibits very low metabolic stability in rat microsomes, with only 1% of the parent compound remaining after 10 minutes.
- Potent and selective histamine H4 receptor inverse agonist.
- IC50 of 19 nM for the H4 receptor.
- Suitable for in vitro studies.
- Exhibits low metabolic stability in rat microsomes in vivo.
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Medchemexpress LLC Methyl pentadecanoate | 7132-64-1 | 256.42 | 5 G
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Methyl pentadecanoate is a fatty acid ester that can be isolated from L. wallichi extracts. It is formed by the condensation of the carboxy group of pentadecanoic acid with the hydroxy group of methanol.
- High purity: 99.51%
- Molecular weight: 256.42
- CAS number: 7132-64-1
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- Structure classification: Lipid
- Initial source: Plants other families
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